Human disease: Calcium signaling in polycystic kidney disease
نویسندگان
چکیده
Polycystic kidney disease results from loss of function of either of two novel proteins, polycystin-1 or polycystin-2. Recent studies show that intracellular calcium signaling is important in kidney development, and define defects in this signaling pathway as the basis of cyst formation in polycystic kidney disease.
منابع مشابه
Regulation of calcium signaling by primary cilia and its role in polycystic kidney disease pathogenesis
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ورودعنوان ژورنال:
- Current Biology
دوره 11 شماره
صفحات -
تاریخ انتشار 2001